[KO Validated] Src Rabbit mAb - A19119

[KO Validated] Src Rabbit mAb

Sizes: 20µl, 100µl

Catalogue Numbers: A19119-20, A19119-100

Citations, Manuals and SDS Available upon request.

Background: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Synonyms: ASV; SRC1; THC6; c-SRC; p60-Src; rc

GeneID: 6714

Swiss-Prot: P12931

Reactivity: Human, Mouse, Rat

Tested Applications: ELISA, WB, IF/ICC, IP

Calculated Molecular Weight: 60kDa

Observed Molecular Weight: 60kDa

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Src (P12931).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Research Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, Tyrosine kinases, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Cell Adhesion, Cytoskeleton, Microtubules, Actins, Wnt ��-Catenin Signaling Pathway, Immunology Inflammation, Jak-Stat-IL-6 Receptor Signaling Pathway, Cardiovascular, Angiogenesis

Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200 | IP: 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells

Modifications: Unmodified

Conjugate: Unconjugated

Cellular Location: Cell Membrane, Cytoplasm, Mitochondrion Inner Membrane, Nucleus, Cytoskeleton,

Positive Samples: HeLa, Jurkat, Mouse brain, Mouse lung, Rat brain

Keywords: 6714, sc-19, ASV, c SRC, c-SRC, p60 Src, pp60c src, Proto oncogene c Src, SRC, SRC1, THC6, p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, proto-oncogene tyrosine-protein kinase Src, proto-oncogene c-Src, protooncogene SRC, Rous sarcoma, tyrosine kinase pp60c-src, tyrosine-protein kinase SRC-1, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, P12931, SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase, V-Src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog, Proto-Oncogene C-Src, P60-Src, Proto-Oncogene Tyrosine-Protein Kinase Src, Protooncogene SRC, Rous Sarcoma, Tyrosine-Protein Kinase SRC-1, Tyrosine Kinase Pp60c-Src, EC 2.7.10.2, Pp60c-Src, C-SRC, proto-oncogene tyrosine-protein kinase Srcproto-oncogene c-Srcprotooncogene SRC, Rous sarcomatyrosine kinase pp60c-srctyrosine-protein kinase SRC-1v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, rc

Symbol: SRC

Category: Monoclonal Antibodies

Research Use Only