KSP-Cadherin mouse mAb (PT0160)
Sizes: 50µl, 100µl
Catalogue Numbers: RA12251-50, RA12251-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.05% sodium azide.
Store at: -20°C/1 year
Recommended Dilution: IHC-p 1:100-500, IF 1:100-500
Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Alternative Names: Cadherin-16 (Kidney-specific cadherin, Ksp-cadherin)
Background: cadherin 16 (CDH16) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],
Applications: IHC-p, IF (paraffin section)
Species Cross-Reactivity: Human
GeneID (Human): 1014
SWISS: O75309
Source: Mouse
Immunogen: Synthesized peptide derived from human KSP-Cadherin
Category: Monoclonal
Research Use Only