LIN28A Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A22648PM-20, A22648PM-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
Category: Monoclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 23kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 79727
SWISS: Q9H9Z2
Alternate Names: CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:10000 - 1:60000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Neuroscience, Stem Cells, Embryonic Stem Cells.
NCBI Alias: LIN28A
Research Use Only