PARP2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A5945-20, A5945-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
Synonyms: ARTD2; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2; PARP2
GeneID: 10038
Swiss-Prot: Q9UGN5
Reactivity: Human
Calculated Molecular Weight: 66kDa
Observed Molecular Weight: 60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 484-583 of human PARP2 (Q9UGN5).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cell Biology Developmental Biology, Cell Cycle, Centrosome
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: A-549, SH-SY5Y
Cellular Location: Chromosome, Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.