PAX3 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22293-20, A22293-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Synonyms: WS1; WS3; CDHS; HUP2; PAX-3; PAX3
GeneID: 5077
Swiss-Prot: P23760
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 53kDa
Observed Molecular Weight: 53kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAX3 (NP_852122.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cell Biology Developmental Biology, Apoptosis, Stem Cells, Mesenchymal Stem Cells, Neural Stem Cells
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Nucleus
Positive Samples: 293T, U-251MG, Mouse brain, Rat brain
Keywords: sc-34918, sc-34916, sc-7749, sc-7748, sc-25409, CDHS, HUP2, paired box 3, Paired box protein Pax 3, PAX3, WS1, WS3, paired box protein Pax-3, paired box homeotic gene 3, paired domain gene 3, paired domain gene HuP2, transcriptional factor PAX3, P23760, 5077, Paired box protein Pax-3, Paired box protein Pax3, sc34918, sc 34918, sc34916, sc 34916, sc7749, sc 7749, sc7748, sc 7748, sc25409, sc 25409
Symbol: PAX3
Category: Monoclonal Antibodies
Research Use Only