Paxillin Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB12179-50, MB12179-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P49023
Host: Rabbit
Reactivity: Human, Rat, Hamster
Applications: WB, IHC-P, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Background: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 65 kDa; Observed MW: 65 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Paxillin in Hela lysates using Paxillin antibody., Western blot analysis of Paxillin in CHO-K1, C6 lysates using Paxillin antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Paxillin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: PXN; Paxillin
Immunogen: A synthetic peptide of human Paxillin
Conjugate: Unconjugated
Modification: Unmodified