PBR/TSPO Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4881-20, A4881-100
Citations, Manuals and SDS Available upon request.
Background: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.
Synonyms: DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18; TSPO1; PBR/TSPO
GeneID: 706
Swiss-Prot: P30536
Reactivity: Human, Mouse
Calculated Molecular Weight: 19kDa
Observed Molecular Weight: 18kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 70-169 of human PBR/TSPO (P30536).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Lipid Metabolism, Cholesterol Metabolism, Neuroscience, Calcium Signaling, Cardiovascular, Lipids
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, 293T, Mouse lung, Mouse liver, Mouse spleen
Cellular Location: Mitochondrion Membrane, Multi-pass Membrane Protein
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.