PCBD1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9426-20, A9426-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Synonyms: PCD; PHS; DCOH; PCBD; PCBD1
GeneID: 5092
Swiss-Prot: P61457
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 12kDa
Observed Molecular Weight: 12kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-104 of human PCBD1 (P61457).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: 293T, Hep G2, Mouse liver, Mouse kidney, Mouse pancreas, Rat liver, Rat kidney
Cellular Location: Cytoplasm, Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.