PCBP2 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11377-50, MB11377-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q15366
Host: Rabbit
Reactivity: Mouse,Rat
Applications: WB,IP
All Applications: WB: 1/500-1/1000 IP: 1/20
Background: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PCBP2/hnRNP E2 in C6, 3T3Lysates using PCBP2 antibody.
Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 35-45 kDa
Specificity: IgG
Alternative Name: HNRPE2; HNRNPE2; hnRNP-E2
Immunogen: A synthetic peptide of human PCBP2
Conjugate: Unconjugated
Modification: Unmodified