PCNA Monoclonal Antibody (12D10)
Sizes: 50μL, 100μL
Catalogue Number: RA10511-50, RA10511-100
Citations, Manuals and MSDS Available upon request.
Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: WB: 1:5000 IHC: 1:200 IF 1:200
Alternative Names: PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin
Background: proliferating cell nuclear antigen(PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Applications: WB; IF/ICC; IHC-p
Species Cross-Reactivity: Human; Rat; Mouse
Molecular Weight: 29
GeneID (Human): 5111
Protein MW (KDa): 29
SWISS: P12004
Source: Mouse
Research Use Only