PD-L1 (CD274) Rabbit Monoclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Sizes: 50µl, 100µl
Catalogue Numbers: BS40368-50, BS40368-100
Swiss-Prot: Q9NZQ7
Host: Rabbit
PD-L1 (CD274) Rabbit Monoclonal Antibody-BS40368
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
All Applications: WB 1:100~1:500 IHC 1:50~1:100
Background: Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
Purification and Purity: Affinity-chromatography
Specificity: PD-L1 (CD274) Antibody detects endogenous levels of total PD-L1 (CD274)
Bioworld Molecular Weight: 46kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate., Immunohistochemical analysis of paraffin-embedded human thymoma, using PD-L1 (CD274) Antibody.
Alternative Name: B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;
Immunogen: A synthesized peptide derived from human PD-L1 (CD274)
Modification: Unmodified
Conjugate: Unconjugated