PDGF B Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11383-50, MB11383-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P01127
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB,IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA .
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PDGF B in mouse brain, rat brainLysates using PDGF B antibody.
Bioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 27 kDa
Specificity: IgG
Alternative Name: PDGFB; PDGF2; SIS; Platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-Sis; Becaplermin
Immunogen: A synthetic peptide of human PDGF B
Conjugate: Unconjugated
Modification: Unmodified