PE Rabbit anti-Human CD207/Langerin Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A28251-100, A28251-200, A28251-500
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 37kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 50489
SWISS: Q9UJ71
Alternate Names: CLEC4K
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Immunology Inflammation, CDs
NCBI Alias: CD207
Modifications: Unmodified
Conjugate: PE. Ex:565nm. Em:574nm.
Clone Number Info: ARC77401
Research Use Only