PE Rabbit anti-Human Complement C3 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27173-100, A27173-200, A27173-500
Citations, Manuals and MSDS Available upon request.
Background: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human
Protein Weight: 187kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 718
SWISS: P01024
Alternate Names: ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway
NCBI Alias: C3
Modifications: Unmodified
Conjugate: PE. Ex:565nm. Em:574nm.
Clone Number Info: ARC71933
Research Use Only