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PE Rabbit anti-Mouse TNF-α Monoclonal Antibody - A27472

PE Rabbit anti-Mouse TNF-α Monoclonal Antibody - A27472

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PE Rabbit anti-Mouse TNF-α Monoclonal Antibody

Sizes: 100T, 2 x 100T, 5 x 100T

Catalogue Numbers: A27472-100, A27472-200, A27472-500

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants.

Category: Monoclonal Antibodies

Application: FC (intra)

Cross Reactivity: Mouse

Protein Weight: 26kDa Immunogen: Recombinant protein (or fragment).

Species: Mouse

GeneID: 21926

SWISS: P06804

Alternate Names: DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.

Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume

Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Growth factors, Death Receptor Signaling Pathway, Endocrine Metabolism, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Immunology Inflammation, Cytokines, NF-kB Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Cardiovascular

NCBI Alias: Tnf

Modifications: Unmodified

Conjugate: PE. Ex:565nm. Em:574nm.

Clone Number Info: ARC54412

Research Use Only