PFKM Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A3671-20, A3671-100
Citations, Manuals and SDS Available upon request.
Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Synonyms: GSD7; PFK1; PFKA; PFKX; PFK-1; PFK-A; ATP-PFK; PPP1R122; PFKM
GeneID: 5213
Swiss-Prot: P08237
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 85kDa
Observed Molecular Weight: 90kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Fructose 6 Phosphate Kinase (P08237).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Carbohydrate metabolism, Warburg Effect
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, RD, Mouse skeletal muscle, Mouse brain, Rat skeletal muscle
Cellular Location: Cytoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.