Phospho-delta 1 Catenin (Thr916) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11855-50, MB11855-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: O60716
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 108 kDa; Observed MW: 100 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-delta 1 Catenin/CAS in MCF-7, U251, C2C12 lysates using Phospho-delta 1 Catenin antibody., Immunocytochemistry analysis of delta 1 Catenin/CAS in hela using delta 1 Catenin/CAS antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-delta 1 Catenin/CAS antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr916 of human delta 1 Catenin/CAS
Conjugate: Unconjugated
Modification: Phosphorylated