Phospho-Dishevelled 2 (Ser143) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10834-50, MB10834-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: O14641
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Dishevelled 2 in K562Lysates using Phospho-Dishevelled 2 antibody.
Bioworld Molecular Weight: Calculated MW: 79 kDa; Observed MW: 90-95 kDa
Specificity: IgG
Alternative Name: DSH homolog 2
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2
Conjugate: Unconjugated
Modification: Phosphorylated