Phospho-ERK 1/2 (Y222/205)Mouse Monoclonal Antibody (4G3)
Sizes: 50µl, 100µl
Catalogue Numbers: RA10644-50, RA10644-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilution: IHC-p 1:100-200
Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Alternative Names: MAPK1/MAPK3
Background: mitogen-activated protein kinase 3 (MAPK3) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Applications: IHC-p, IF (paraffin section)
Species Cross-Reactivity: Human, Rat, Mouse
GeneID (Human): 5594/5595
SWISS: P27361/P28482
Source: Mouse
Immunogen: Synthetic Peptide of Phospho-ERK 1/2 (Y222/205) at AA range of 140-220
Category: Monoclonal
Research Use Only