Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB3271-50, MB3271-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: P27361/P28482
Host: Mouse
Reactivity: Human, Rat, Mouse
Applications: IHC-P
All Applications: IHC: 1/50-1/100
Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG1
Bioworld Molecular Weight: -
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using Phospho-ERK1/2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: MAPK1/MAPK3
Immunogen: Synthetic peptide conjugated to KLH.
Conjugate: Unconjugated
Modification: Phosphorylated