Phospho-GSK3 beta (Ser9) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10428-50, MB10428-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P49841
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-GSK3 beta in K562, C6, 3T3, Hela lysates using Phospho-GSK3 beta antibody., Immunocytochemistry analysis of Phospho-GSK3 beta in Hela using Phospho-GSK3 beta antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Phospho-GSK3 beta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser9 of human GSK3 beta
Conjugate: Unconjugated
Modification: Phosphorylated