Phospho-IGF1 Receptor (Tyr1166) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11111-50, MB11111-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P08069
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB,IP
All Applications: WB: 1/500-1/1000 IP: 1/20
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-IGF1R in C6, 3T3, HelaLysates using Phospho-IGF1 Receptor antibody.
Bioworld Molecular Weight: Calculated MW: 155 kDa; Observed MW: 95 kDa
Specificity: IgG
Alternative Name: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R
Conjugate: Unconjugated
Modification: Phosphorylated