Phospho-MDM2 (Ser166) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10430-50, MB10430-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q00987
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 55 kDa; Observed MW: 90 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-MDM2 in Jurkat, C6, Hela lysates using Phospho-MDM2 antibody., Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Phospho-MDM2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: Double minute 2 protein; Hdm2; Oncoprotein Mdm2
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser166 of human MDM2
Conjugate: Unconjugated
Modification: Phosphorylated