Phospho-Phospholamban (Ser16) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11410-50, MB11410-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P26678
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-lamban in mouse heartLysates using Phospho-Phospho-lamban antibody.
Bioworld Molecular Weight: Calculated MW: 6 kDa; Observed MW: 12,24 kDa
Specificity: IgG
Alternative Name: PLN; PLB; Cardiac phospholamban; PLB
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban
Conjugate: Unconjugated
Modification: Phosphorylated