PKC beta 1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11424-50, MB11424-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P05771
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Background: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 77 kDa; Observed MW: 77 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunocytochemistry analysis of PKC beta 1 in K562 using PKC beta 1 antibody, and DAPI., Western blot analysis of PKC beta 1 in rat brain lysates using PKC beta 1 antibody., Western blot analysis of PKC beta 1 in K562 lysates using PKC beta 1 antibody
Alternative Name: PRKCB; PKCB; PRKCB1; Protein kinase C beta type; PKC-B; PKC-beta
Immunogen: A synthetic peptide of human PKC beta 2
Conjugate: Unconjugated
Modification: Unmodified