PKM1/2 Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A27199PM-20, A27199PM-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Category: Monoclonal Antibodies
Applications: WB, IF/ICC, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 58kDa
Observed Molecular Weight: 60kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 5315
SWISS: P14618
Alternate Names: PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:10000 - 1:100000 IF/ICC, 1:200-1:400 IF-P, 1:200-1:400 IHC-P, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Carbohydrate metabolism, Warburg Effect.
NCBI Alias: PKM
Research Use Only