PLCB2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22526-20, A22526-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
Synonyms: PLC-beta-2; PLCB2
GeneID: 5330
Swiss-Prot: Q00722
Reactivity: Human, Mouse
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 134kDa
Observed Molecular Weight: 150kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_004564.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Cell Biology Developmental Biology, Cytoskeleton, Actins, Endocrine Metabolism, Lipid Metabolism, AMPK Signaling Pathway, Neuroscience, Neurodegenerative Diseases
Recommended Dilutions: WB: 1:1000 - 1:5000 | IHC-P: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytosol, G-Protein beta/gamma-subunit Complex, Golgi Apparatus, neuronal dense core Vesicle, Plasma Membrane,
Positive Samples: HEL, Mouse thymus
Keywords: 5330, sc-31759, sc-31757, sc-206, sc-9018, PLCB2, PLC-beta-2, phospholipase C beta 2, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-2, phosphoinositide phospholipase C-beta-2, Q00722, Phospholipase C Beta 2, Phosphoinositide Phospholipase C-Beta-2, PLC-Beta-2, 1-Phosphatidylinositol 4, 5-Bisphosphate Phosphodiesterase Beta-2, Phospholipase C, Beta 2, Phospholipase C-Beta-2, EC 3.1.4.11, PLCbeta-2, PLC beta-2, sc31759, sc 31759, sc31757, sc 31757, sc206, sc 206, sc9018, sc 9018
Symbol: PLCB2
Category: Monoclonal Antibodies
Research Use Only