PLK1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11434-50, MB11434-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P53350
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Background: Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 68 kDa; Observed MW: 68 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PLK1 in Jurkat, C6 lysates using PLK1 antibody., Immunocytochemistry analysis of PLK1 in Hela using PLK1 antibody, and DAPI
Alternative Name: PLK1; PLK; Serine/threonine-protein kinase PLK1; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13
Immunogen: A synthetic peptide of human PLK1
Conjugate: Unconjugated
Modification: Unmodified