PLK1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22322-20, A22322-100
Citations, Manuals and SDS Available upon request.
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Synonyms: PLK; STPK13; PLK1
GeneID: 5347
Swiss-Prot: P53350
Reactivity: Human, Mouse, Rat, Monkey
Tested Applications: ELISA, WB
Calculated Molecular Weight: 68kDa
Observed Molecular Weight: 62kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 272-495 of human PLK1 (NP_005021.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Cancer, Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Cell Cycle Control-G2 M DNA Damage Checkpoint
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Chromosome, Cytoplasm, MidBody, Nucleus, centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center, Spindle,
Positive Samples: HeLa, Jurkat, COS-7, Mouse testis
Keywords: 5347, sc-6355, sc-5585, PLK, PLK 1, PLK1, Polo like kinase 1, STPK13, polo like kinase 1, serine/threonine-protein kinase PLK1, PLK-1, cell cycle regulated protein kinase, polo (Drosophia)-like kinase, serine/threonine-protein kinase 13, P53350, Plk, Polo Like Kinase 1, Serine/Threonine-Protein Kinase 13, Polo-Like Kinase 1, Serine/Threonine-Protein Kinase PLK1, Cell Cycle Regulated Protein Kinase, Polo-Like Kinase (Drosophila), Polo (Drosophia)-Like Kinase, EC 2.7.11.21, sc6355, sc 6355, sc5585, sc 5585
Symbol: PLK1
Category: Monoclonal Antibodies
Research Use Only