PLOD3 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21066-20, A21066-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
Synonyms: LH3; PLOD3
GeneID: 8985
Swiss-Prot: O60568
Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Calculated Molecular Weight: 85kDa
Observed Molecular Weight: 85kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-306 of human PLOD3 (NP_001075.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling
Recommended Dilutions: WB: 1:1000 - 1:5000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Lumenal side, Peripheral Membrane Protein, Rough Endoplasmic Reticulum Membrane
Positive Samples: HepG2, MCF7, BxPC-3, Jurkat, Mouse brain
Keywords: 8985, sc-50071, sc-50072, sc-50070, sc-98453, LH3, Lysyl hydroxylase 3, PLOD3, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, lysine hydroxylase 3, lysyl hydroxlase 3, lysyl hydroxylase 3, O60568, Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3, Lysyl Hydroxylase 3, Lysyl Hydroxlase 3, Lysine Hydroxylase 3, EC 1.14.11.4, sc50071, sc 50071, sc50072, sc 50072, sc50070, sc 50070, sc98453, sc 98453
Symbol: PLOD3
Category: Monoclonal Antibodies
Research Use Only