PLZF Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21185-20, A21185-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
Synonyms: PLZF; ZNF145
GeneID: 7704
Swiss-Prot: Q05516
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 74kDa
Observed Molecular Weight: 80kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 199-300 of human PLZF (NP_005997.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Cell Biology Developmental Biology, Apoptosis, Stem Cells, Germline Stem Cells, Hematopoietic Progenitors
Recommended Dilutions: WB: 1:2000 - 1:10000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Nucleus
Positive Samples: 293F, Mouse heart, Rat brain
Keywords: 7704, sc-11146, sc-22839, PLZF, ZBTB16, Zinc finger protein 145, Zinc finger protein PLZF, ZNF145, zinc finger and BTB domain containing 16, zinc finger and BTB domain-containing protein 16, promyelocytic leukaemia zinc finger, zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia), zinc finger protein PLZF, Q05516, Zinc Finger And BTB Domain Containing 16, Zinc Finger Protein 145 (Kruppel-Like, Expressed In Promyelocytic Leukemia), Promyelocytic Leukaemia Zinc Finger, Zinc Finger Protein PLZF, Zinc Finger And BTB Domain-Containing Protein 16, Promyelocytic Leukemia Zinc Finger Protein, Zinc Finger Protein 145, sc11146, sc 11146, sc22839, sc 22839
Symbol: ZBTB16
Category: Monoclonal Antibodies
Research Use Only