PMEL17 / GP100 Rabbit Monoclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Sizes: 50µl, 100µl
Catalogue Numbers: BS40062-50, BS40062-100
Swiss-Prot: P40967
Host: Rabbit
PMEL17 / GP100 Rabbit Monoclonal Antibody-BS40062
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reactivity: Human
Applications: WB, IHC
All Applications: WB 1:500~1:2000 IHC 1:50~1:200
Background: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Purification and Purity: Affinity-chromatography
Specificity: PMEL17 / GP100 Antibody detects endogenous levels of total PMEL17 / GP100
Bioworld Molecular Weight: 100kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PMEL17 / GP100 expression in human melanoma lysate., Immunohistochemical analysis of paraffin-embedded human melanoma, using PMEL17 / GP100 Antibody.
Alternative Name: PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV;
Immunogen: A synthesized peptide derived from human PMEL17 / GP100
Modification: Unmodified
Conjugate: Unconjugated