PNKP Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21145-20, A21145-100
Citations, Manuals and SDS Available upon request.
Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Synonyms: PNK; AOA4; MCSZ; CMT2B2; EIEE10; PNKP
GeneID: 11284
Swiss-Prot: Q96T60
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 57kDa
Observed Molecular Weight: 60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of Human PNKP (NP_009185.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Nucleus
Positive Samples: SK-BR-3, Jurkat, U-937, Mouse spleen, Rat testis
Keywords: 11284, PNKP, AOA4, EIEE10, MCSZ, PNK, polynucleotide kinase 3'-phosphatase, bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP), Q96T60, Polynucleotide Kinase 3', -Phosphatase, DNA 5-Kinase/3-Phosphatase, Homo Sapiens Polynucleotide Kinase 3-Phosphatase (PNKP), Bifunctional Polynucleotide Phosphatase/Kinase, Polynucleotide Kinase 3-Phosphatase, Polynucleotide Kinase-3-Phosphatase, DNA 5 kinase/3 phosphatase
Symbol: PNKP
Category: Monoclonal Antibodies
Research Use Only