PODXL Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4554-20, A4554-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Synonyms: PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1; PODXL
GeneID: 5420
Swiss-Prot: O00592
Reactivity: Human
Calculated Molecular Weight: 59kDa
Observed Molecular Weight: 200-400kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-479 of human PODXL (O00592).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Cancer, Tumor biomarkers, Signal transduction, Cell Bbiology developmental biology, Cytoskeleton, Extracellular matrix, Stem cells, Hematopoietic progenitors, Cardiovascular
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HCT 116, 293T, U-251MG
Cellular Location: apical Plasma Membrane, Cytoplasm, Extra Cellular Exosome, Extra Cellular Space, microvillus Membrane, NucleolusPlasma Membrane, slit diaphragm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.