POT1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11442-50, MB11442-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q9NUX5
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1/500-1/1000
Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of POT1 in K562, C6, 3T3Lysates using POT1 antibody.
Bioworld Molecular Weight: Calculated MW: 71 kDa; Observed MW: 71 kDa
Specificity: IgG
Alternative Name: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Immunogen: A synthetic peptide of human POT1
Conjugate: Unconjugated
Modification: Unmodified