POU5F1/OCT4 Mouse Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA11862-50, RA11862-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:1000
Alternative Names: MGC22487;Oct 3;Oct 4;Oct-3;Oct-4;OCT3;Oct4;Octamer binding protein 3;Octamer binding protein 4;Octamer binding transcription factor 3;Octamer-binding protein 3;Octamer-binding protein 4;Octamer-binding transcription factor 3;OTF 3;OTF 4;OTF-3;OTF3;OTF4; PO5F1_HUMAN;POU class 5 homeobox 1;POU domain class 5 transcription factor 1;POU domain transcription factor OCT4;POU domain, class 5, transcription factor 1;POU5F1.
Background: POU class 5 homeobox 1(POU5F1) Homo sapiens This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013],
Applications: WB
Species Cross-Reactivity: Mouse
Molecular Weight: 45
GeneID (Human): 18999
Protein MW (KDa): 45
SWISS: Q01860
Source: Mouse
Research Use Only