PP1α Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA11865-50, RA11865-100
Citations, Manuals and MSDS Available upon request.
Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Alternative Names: PPP1CA; PPP1A; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; PP-1A
Background: protein phosphatase 1 catalytic subunit alpha(PPP1CA) Homo sapiens The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Applications: WB; IF/ICC
Species Cross-Reactivity: Human; Mouse; Rat; Bovine; Chicken; Pig; Rabbit; Zebrafish
GeneID (Human): 5499
SWISS: P62136
Source: Mouse
Research Use Only