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Presenilin 1 Monoclonal Antibody-MB11454

Presenilin 1 Monoclonal Antibody-MB11454

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Presenilin 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11454-50, MB11454-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P49768

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 53 kDa; Observed MW: 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Presenilin 1 in SKOV-3 using Presenilin 1 antibody, and DAPI., Western blot analysis of Presenilin 1/PS1 in mouse colon, mouse gastric lysates using Presenilin 1/PS1 antibody., Western blot analysis of Presenilin 1/PS1 in Hela, C6, Jurkat lysates using Presenilin 1/PS1 antibody

Alternative Name: PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182

Immunogen: A synthetic peptide of human Presenilin 1

Conjugate: Unconjugated

Modification: Unmodified