PRG2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A25008-20, A25008-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: PRG2; BMPG; MBP; MBP1; proMBP; bone marrow proteoglycan
GeneID: 5553
Swiss-Prot: P13727
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 23kDa/25kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2(NP_002719.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Immunology；Adaptive Immunity；T Cells；Cytotoxic Cells；Cell Type Markers；CD；NK Cells；Tags & Cell Markers；Other Cell Types
Recommended Dilutions: WB: 1:1000 - 1:5000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasmic Vesicle, Secreted, Secretory Vesicle
Positive Samples: Rat spleen
Keywords: sc-33938, sc-34012, sc-33556, BMPG, Bone marrow proteoglycan, EMBP, MBP, MBP1, PRG2, Proteoglycan 2, proMBP, proteoglycan 2, pro eosinophil major basic protein, bone marrow proteoglycan, eosinophil granule major basic protein, eosinophil major basic protein, natural killer cell activator, proteoglycan 2 preproprotein, bone marrow (natural killer cell activator, eosinophil granule major basic protein), P13727, 5553
Symbol: PRG2
Category: Monoclonal Antibodies
Research Use Only