PRMT1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4502-20, A4502-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Synonyms: ANM1; HCP1; IR1B4; HRMT1L2; PRMT1
GeneID: 3276
Swiss-Prot: Q99873
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 45kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRMT1 (Q99873).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, Nuclear Receptor Signaling, Cancer, Tumor suppressors, p53 pathway, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SW620, Mouse brain
Cellular Location: Cytoplasm, Nucleus, Cytosol, Nucleoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.