Rac3 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11499-50, MB11499-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P60763
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 21 kDa; Observed MW: 21 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RAC3 in K562, rat Brain lysates using Rac3 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using RAC3 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)
Immunogen: A synthetic peptide of human RAC3
Conjugate: Unconjugated
Modification: Unmodified