Rad18 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4339-20, A4339-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Synonyms: RNF73; Rad18
GeneID: 56852
Swiss-Prot: Q9NS91
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 56kDa
Observed Molecular Weight: 70kDa/90kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rad18 (Q9NS91).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Ubiquitin
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, A-549, MCF7, K-562, Mouse testis, Mouse brain, Mouse spleen, Rat testis
Cellular Location: Cytoplasm, Nucleus, Centrosome, Cytoskeleton, Microtubule Organizing Center,
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.