Rad50 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB12219-50, MB12219-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q92878
Host: Rabbit
Reactivity: Human
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 154 kDa; Observed MW: 154 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Rad50 in Hela, A549, HL-60 lysates using Rad50 antibody., Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using Rad50 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: RAD50; DNA repair protein RAD50; hRAD50
Immunogen: Recombinant protein of human Rad50
Conjugate: Unconjugated
Modification: Unmodified