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Rad51 mouse mAb - RA11925

Rad51 mouse mAb - RA11925

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$198.00 USD
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$198.00 USD
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Rad51 mouse mAb

Sizes: 50µl, 100µl

Catalogue Numbers: RA11925-50, RA11925-100

Citations, Manuals and MSDS Available upon request.

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Store at: -20°C/1 year

Recommended Dilution: wb 1:1000

Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Alternative Names: BRCA1/BRCA2 containing complex, subunit 5 , BRCC 5 , BRCC5 , DNA repair protein RAD51 homolog 1 , DNA repair protein rhp51 , HRAD51 , HsRad51 , HsT16930 , MRMV2 , Rad 51 , RAD51 , RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) , RAD51 homolog A , RAD51 homolog , RAD51 recombinase , RAD51, S. cerevisiae, homolog of , RAD51_HUMAN , RAD51A , RECA , RecA like protein , RecA, E. coli, homolog of , Recombination protein A.

Background: RAD51 recombinase (RAD51) Homo sapiens The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009],

Applications: WB

Species Cross-Reactivity: Human, Mouse, Rat, Monkey

GeneID (Human): 5888

SWISS: Q06609

Source: Mouse

Immunogen: Recombinant protein of human Rad51.

Category: Monoclonal

Research Use Only