Rad52 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A5186-20, A5186-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Synonyms: RAD52; DNA repair protein RAD52 homolog; Rad52
GeneID: 5893
Swiss-Prot: P43351
Reactivity: Human
Calculated Molecular Weight: 13kDa/15kDa/25kDa/46kDa
Observed Molecular Weight: 50kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 319-418 of human Rad52 (P43351).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cell Biology Developmental Biology, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, 293T, PC-3
Cellular Location: Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.