RAGE Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11506-50, MB11506-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q15109
Host: Rabbit
Reactivity: Mouse
Applications: WB
All Applications: WB: 1/500-1/1000
Background: The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RAGE in mouse lungLysates using RAGE antibody.
Bioworld Molecular Weight: Calculated MW: 43 kDa; Observed MW: 55 kDa
Specificity: IgG
Alternative Name: AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products
Immunogen: A synthetic peptide of human RAGE
Conjugate: Unconjugated
Modification: Unmodified