RAIDD Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB12221-50, MB12221-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P78560
Host: Rabbit
Reactivity: Human
Applications: WB, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Background: The receptor interacting protein RIP is a death domain-containing serine/threonine kinase which associates with FAS or the TNF-R1 binding protein TRADD. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 23 kDa; Observed MW: 23 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RAIDD in Hela, A549, MCF-7, 293T lysates using RAIDD antibody., Immunocytochemistry analysis of RAIDD in hela using RAIDD antibody, and DAPI
Alternative Name: CRADD; MGC9163; RAIDD; Death adaptor molecule RAIDD; Death domain containing protein CRADD
Immunogen: A synthetic peptide of human RAIDD
Conjugate: Unconjugated
Modification: Unmodified