RAP80 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB12223-50, MB12223-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q96RL1
Host: Rabbit
Reactivity: Human
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 80 kDa; Observed MW: 80 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunocytochemistry analysis of RAP80 in Hela using RAP80 antibody, and DAPI., Western blot analysis of RAP80 in Hela, A549, HL-60, U2OS lysates using RAP80 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using RAP80 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: RAP80; X2HRIP110
Immunogen: A synthetic peptide of human RAP80
Conjugate: Unconjugated
Modification: Unmodified