Recombinant FKBP52 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81469-50, E-AB-81469-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: FKBP52
Target Synonym: 51 kDa FK506-binding protein; 52 kDa FK506 binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4; FK506-binding protein 4; FKBP 4; FKBP 52; FKBP 59; FKBP-4; FKBP-52; FKBP4; FKBP4; FKBP51; FKBP52 protein; FKBP59; HBI; Hsp 56; HSP binding immunophilin; HSP-binding immunophilin; Hsp56; Immunophilin FKBP52; N-terminally processed; p52; p59; p59 protein; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP4; Peptidylprolyl cis trans isomerase; PPIase; PPIase FKBP4; Rotamase; T cell FK506 binding protein 59kD
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat, Hamster
Application: WB, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R03-4A3
UNIProt ID: Q02790
Background: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human FKBP52
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:5000 IF 1:20-1:50
Calculated MW: 52kDa
Observed MW: 52kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only