Recombinant FTO Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81470-50, E-AB-81470-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: FTO
Target Synonym: AlkB homolog 9; ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; Fat mass and obesity-associated protein; FATSO; MOUSE; HOMOLOG OF; Fto; FTO; GDFD; KIAA1752; mKIAA1752; Protein fatso
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC-P, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-8G5
UNIProt ID: Q9C0B1
Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human FTO
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:2000-5000 IHC 1:50-1:100 IF 1:20-1:100
Calculated MW: 58kDa
Observed MW: 58kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only